References for Cataract Prevention - Natural Medical Protocols

Below are supplemental abstracts and references of research that support the conclusions on the treatment for Cataract Prevention

Free Radicals

Garrett DG. "Free radicals and antioxidants: what is their clinical role?" J Am Acad of Phys Assist. June, 1997;58-82.

Straatsma B. "Aging-related cataract: Laboratory investigation and clinical management." Annals Int Med. 1985;102:82-92.

Animal Fats

Lu M, et al. "Prospective study of dietary fat and risk of cataract extraction among US women." Am J Epidemiol. May,2005;161(10):948:59.

Lu M, et al. "Dietary fat intake and early age-related lens opacities." Am J Clin Nutr. 2005;81:773-779.

Liu RH. "Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals." Am J Clin Nutr. 2003;78(Suppl):517S-520S.

Tavani A, et al. "Food and nutrient intake and risk of cataract." Ann Epidem. 1996;6:41-46.

Dairy Products

Couet C, et al. "Lactose and cataract in humans: a review." J Am Coll Nutr. 1991;10:79-86.

Alcohol

Trevithick CC, et al. "Is ethanol an important antioxidant in alcoholic beverages associated with risk reduction of cataract and atherosclerosis?" Redox Report. 1999;4(3):89-93.

Vitamin and Mineral References

Vitamin B1 (Thiamine)

Bakker SJL. "Low thiamine intake and risk of cataract." Ophthalmol. 2001;108(7):1167.

Antioxidants

Rodriguez-Rodriguez E, et al. "The relationship between antioxidant nutrient intake and cataracts in older people." Intl J Vit Nutr Res. 2006; 76(6):359-366.

Taylor A, et al. "Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities." Am J Clin Nutr. 2002;75:540-549.

Casado A, et al. "Antioxidant enzyme levels in red blood cells from cataract patients." Gerontol. 2001;47:186-188.

Age-Related Eye Disease Study Research Group. "A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS Report No. 9." Arch Ophthalmol. October,2001;119:1439-1452.

Gale CR, et al. "Plasma antioxidant vitamins and carotenoids and age-related cataract." Ophthalmol. November,2001;108(11):1992-1998.

Taylor A, Hobbs M."2001 assessment of nutritional influences on risk for cataract." Nutr. 2001;17:845-857.

Jacques PF, et al. "Long-term nutrient intake and early age-related nuclear lens opacities." Arch Ophthalmol. July,2001;119:1009-1019.

Wu S-Y, Leske MC. "Antioxidants and cataract formation: a summary review." Int Ophthalmol Clin. Fall,2000;40(4):71-81.

Ottonello S, et al. "Oxidative stress and age-related cataract." Ophthalmologica. 2000;214:78-85.

Chasan-Taber L, et al. "A prospective study of vitamin supplement intake and cataract extraction among u.s. women." Epidemiol. November,1999;10(6):679-684.

Christen WG. "Antioxidant vitamins and age-related eye disease." Proc Assoc Am Physicians. January/February,1999;11(1):16-21.

Delcourt C, et al. "Associations of antioxidant enzymes with cataract and age-related macular degeneration." Ophthalmol. February,1999;106(2):215-222.

Meltzer GE, Kravets BZ. "Diet, nutrition, and diseases of the eye." J App Nutr. 1998;50(1 & 2):17-47.

Vitamin C

Yoshida M, et al. "Prospective study showing that dietary vitamin C reduced the risk of age-related cataracts in a middle-aged Japanese population." Eur J Nutr. Jan30,2007.

Valero MP, et al. "Vitamin C is associated with reduced risk of cataract in a Mediterranean population." J Nutr. 2002;132:1299-1306.

Mares-Perlman JA, et al. "Vitamin supplement use and incident cataracts in a population-based study." Arch Opthalmol. November,2000;118:1556-1563.

van der Pols JC. "A possible role for vitamin C in age-related cataract." Proc Nutr Soc. 1999;58:295-301.

Simon JA, Hudes ES. "Serum ascorbic acid and other correlates of self-reported cataract among older americans." J Clin Epidemiol. 1999;52(12):1207-1211.

Carr AC, Frei B. "Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans." Am J Clin Nutr. 1999;69:1086-1107.

Beebe DC. "Nuclear cataracts and nutrition: hope for intervention early and late in life." Invest Ophthalmol Vis Sci. August,1998;39(9):1531-1534.

Tessier F, et al. "Decrease in vitamin C concentration in human lenses during cataract progression." Intl J Vit Nutr Res. 1998;68:309-315.

Wolf AM, Wolf AMD. "Evidence-based use of vitamin and mineral supplementation." Hosp Med. December,1998:53-54.

Jacques PF, et al. "Long-term vitamin C supplement use and prevalence of early age-related lens opacities." Am J Clin Nutr. 1997;66:911-916.

Vitamin E

Neustadt J, Pizzorno J. "Vitamin E and all-cause mortality." Integr Med. Feb/Mar,2005;4(1):14-17.

Jacques PF, et al. "Long-term nutrient intake and 5-year change in nuclear lens opacities." Arch Ophthalmol. April,2005;123:517-526.

Lyle BJ, et al. "Serum carotenoids and tocopherols and incidence of age-related nuclear cataract." Am J Clin Nutr. 1999;69:272-277.

Leske MC, et al. "Antioxidant vitamins and nuclear opacities." Ophthalmol. May,1998;105(5):831-836.

Rouhiainen P, et al. "Association between low plasma vitamin E concentration and progression of early cortical lens opacities." Am J Epidemiol. 1996;144(5):496-500.

Beta-carotene

Vu HT, et al. "Lutein and zeaxanthin and the risk of cataract: the Melbourne visual impairment project." Invest Ophthalmol Vis Sci. 2006;47(9):3783-6.

Cumming RG, et al. "Diet and cataract: The Blue Mountains Eye Study." Ophthalmol. March,2000;107(3):450-456.

"Cataracts, lutein and zeaxanthin." Nutr Week. December10,1999;29(46).

Brown L, et al. "A prospective study of carotenoid intake and risk of cataract extraction in US men." Am J Clin Nutr. 1999;70:517-524.

Chasan-Taber L, et al. "A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women." Am J Clin Nutr. 1999;70:509-516.

Jacques PF. "The potential preventive effects of vitamins for cataract and age-related macular degeneration." Int J Vitam Nutr Res. 1999;69(3):198-205.

Jacques PF, et al. "Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention." Am J Clin Nutr. 1991;53:352s-355s.

Zinc and Copper

Akyol N, et al. "Aqueous humor and serum zinc and copper concentrations of patients with glaucoma and cataract." Br J Opthalmol. 1990;74(11):661-662.

Bhat KS. "Plasma calcium and trace minerals in human sujects with mature cataract." Nutr Rep Int. 1988;37:157-63.

Racz P, et al. "Bilateral cataract in acrodermatitis enteropathica." J Pediatr Ophthalmol Strabismus. 1979;16:180-82.

Selenium

Karakucuk S, et al. "Selenium concentrations in serum, lens and aqueous humor of patients with senile cataract." ACTA Ophthalmologica Scandinavica. 1995;73:323-332.

Supplement References

Tryptophan

Truscott RJW, Wood AM. "Tryptophan metabolism and the reactive metabolite hypothesis for human cataract." University of Wollongong, Australian Cataract Research Foundation. 1995;83-86.

L-Glutathione

Giblin FJ. "Glutathione: a vital lens antioxidant." J Ocul Pharmacol Ther. 2000;16(2):121-135.

Duarte A. Cataract Breakthrough. Int Inst Nat Health Sci. Huntington Beach, CA. 1982.

Rathbun W, et al. "Glutathione metabolic pathway as a scavenging system in the lens." Ophthal Res. 1979;11172-6.

Quercetin

Cogan DG, et al. "Aldose reductase and complications of diabetes." Ann Intern Med. 1984;101:82-91.

Orhan H, et al. "Effects of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats." Toxicology. 1999;Dec 6;139(3):219-32.

Head KA. "Natural therapies for ocular disorders, part two: cataracts and glaucoma." Altern Med Rev. 2001;Apr;6(2):141-66.

Omega-3 Fatty Acids

Townend BS, et al. "Dietary macronutrient intake and five-year incident cataract: The Blue Mountains Eye Study." Am J Opthalmol. Apr23,2007.

Melatonin

Siu AW, et al. "Protective effects of melatonin in experimental free radical-related ocular diseases." J Pineal Res. 2006;40(2):101-109.

Botanical References

Vaccinium myrtillus

Pautler EL, et al. "A pharmacologically potent natural product in the bovine retina." Exp eye Res. 1986;42:285-8.

Curcuma longa

Suryanarayana P, et al. "Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats." Invest Ophthalmol Vis Sci. 2005;46(6):2092-2099.

Awasthi S, et al. "Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses." A J Clin Nutr. 1996;64:761-766.

Homeopathy References

Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.

Other Treatment References

Ultraviolet Radiation

Taylor A. "Nutritional and environmental influences on risk for cataract." Nutr Env Influences on the Eye. 1999;4:53-93. CRC Press. LLC.

Ness AR, et al. "Are we really dying for a tan?" Br Med J. July10,1999;319:114-116.

West SK, et al. "Sunlight exposure and risk of lens opacities in a population-based study: the Salisbury Eye Evaluation Project." JAMA. August26,1998;280(8):714-718.

Rosmini F, et al. "A dose-response effect between a sunlight index and age-related cataracts." Ann Epidemiol. July 1994;4:266-270.

West SK. "Daylight, diet, and age-related cataract." Optometry and Vision Sci. 1993;70(11):869-872.

Smoking

Christen WG, et al. "Smoking cessation and risk of age-related cataract in men." JAMA. August9,2000;284(6):713-716.

"Smoking linked to cataracts: Up to 20% of cases could be caused by tobacco use." Med Trib. September 10,1992;3.

Obesity

Schaumberg DA, et al. "Relations of body fat distribution and height with cataract in men." Am J Clin Nutr. 2000;72:1495-1502.

Caulfield LE, et al. "Anthropometric status and cataract: the Salisbury Eye Evaluation Project." Am J Clin Nutr. 1999;69:237-242.

Statin Drugs and Coenzyme Q10

Bliznakov EG. "Lipid-lowering drugs (statins), cholesterol and coenzyme Q10: The Baycol Case - A modern Pandora's box." Biomed Pharmacother. 2002;56:56-59.

Lead

Schaumberg DA, et al. "Accumulated lead exposure and risk of age-related cataract in men." JAMA. Dec8,2004;292(22):2750-2754.