References for Peptic Ulcers - Natural Medical Protocols

Below are supplemental abstracts and references of research that support the conclusions on the treatment for Peptic Ulcers

Food Elimination

Sicherer SH, "Manifestations of food allergy: evaluation and management." Am Fam Physician. January15,1999;59(2):415-424.

Borok G. "Peptic ulcer and food elimination." CME:VMO. February,1989;7(2):215-216.

Budagovskaia VN, Voitko NE. "Allergic reactions in patients with peptic ulcer; incidence of food and drug allergy." Vopr Pitan. May-June,1984;3:30-33.

Siegel J. "Gastrointestinal ulcer-Arthus reaction!" Ann Allergy. March,1974;32:127-130.

Pollard HM, Stuart GJ. "Experimental reproduction of gastric allergy in human beings with controlled observations on the mucosa." J Allergy. 1942;13:467-473.

Kern RA, Stewart SG. "Allergy in duodenal ulcer: incidence and significance of food hypersensitiveness as observed in 32 patients." J Allergy. 1931;3:51-57.

Fiber

Misciagna G, et al. "Diet and duodenal ulcer." Digest Liver Dis. 2000;32:468-472.

Aldoori WH, et al. "Prospective study of diet and the risk of duodenal ulcer in men." Am J Epidemiol. 1997;145(1):42-50.

Charnow JA. "Vitamin A, fiber may cut risk of duodenal ulcer." Am J Epidemiol. 1997;145:42-50.

Rydning A, et al. "Fiber diet and antacids in the short-term treatment of duodenal ulcer." Gastroenterol. 1985;20:1078-1082.

Rettura G, et al. "Vitamin A protects against aspirin toxicity." J Am Coll Nutr. 1984;3:291-292/Abstract 162.

Rydning A, et al. "Prophylactic effect of dietary fiber in duodenal ulcer disease." Lancet. October2,1982:736-738.

Dairy Products

Marotta RB, Floch MH. "Diet and nutrition in ulcer disease." Med Clin North Am. July,1991;75(4):967-979.

Kumar N, et al. "Effect of milk on patients with duodenal ulcers." Br Med J. 1986;293:666.

Ippoliti AF, et al. "The effect of various forms of milk on gastric-acid secretion: studies in patients with duodenal ulcer and normal subjects." Ann Intern Med. March,1976;84(3):286-289.

Cabbage Juice

Cheney G, et al. "Vitamin U therapy of peptic ulcer." California Med. January,1956;84(1):39-42

Doll R, Pygott F. "Clinical trial of robaden and of cabbage juice in the treatment of gastric ulcer." Lancet. December11,1954:1200-1204.

Cheney G. "Rapid healing of peptic ulcers in patients receiving fresh cabbage juice." Cal Med. 1949;70:10-14.

Spicy Foods, Sugar, Alcohol and Caffeine

Aldori WH, et al. "A prospective study of alcohol, smoking, caffeine and the risk of duodenal ulcer in men." Epidemiol. July,1997;8(4):420-424.

Kang JY, et al. "Chronic upper abdominal pain: site and radiation in various structural and functional disorders and the effect of various foods." Gut. 1992;33:743-748.

Kato I, et al. "A prospective study of gastric and duodenal ulcer and its relation to smoking, alcohol, and diet." Am J Epidemiol. 1992;135(5):521-530.

Katschinski BD, et al. "Duodenal ulcer and refined carbohydrate intake: a case-control study assessing dietary fibre and refined sugar intake." Gut. 1990;31(9):993-996.

Rogers C, et al. "Role for leukotrienes in the pathogenesis of hemorrhagic gastric mucosal lesions induced by ethanol or HCl in the rat." Gastroenterol. May,1986;90(5 part 2):1797.

Lenz HJ, et al. "Wine and five percent ethanol are potent stimulants of gastric acid secretion in humans." Gastroenterol. November,1983;85(5):1082-1087.

McArthur K, et al. "Relative stimulatory effects of commonly ingested beverages on gastric acid secretion in humans." Gastroenterol. July,1982;83(1 part 2):199-203.

Vitamin and Mineral References

Vitamin A

Charnow JA. "Vitamin A, fiber may cut risk of duodenal ulcer." Am J Epidemiol. 1997;145:42-50.

Mahmood T, et al. "Prevention of duodenal ulcer formation in the rat by dietary vitamin a supplementation." J P E N. January/February,1986;10(1):74-77.

Rydning A, et al. "Fiber diet and antacids in the short-term treatment of duodenal ulcer." Gastroenterol. 1985;20:1078-1082.

Rettura G, et al. "Vitamin A protects against aspirin toxicity." J Am Coll Nutr. 1984;3:291-292/Abstract 162.

Patty I, et al. "Cytoprotective effect of vitamin A and its clinical importance in the treatment of patients with chronic gastric ulcer." Int J Tiss Reac. 1983;5(3):301-307.

Patty I, et al. "Controlled trial of vitamin A therapy in gastric ulcer." Lancet. October16,1982:876.

Vitamin B12

Kaptan K, et al. "Helicobacter pylori - is it a novel causative agent in vitamin B12 deficiency?" Arch Intern Med. 2000;160:1349-1353.

Swain R. "An update on vitamin B12 metabolism and deficiency states." J Fam Prac. December,1995;41(6):595-600.

Vitamin C

Rokkas T, et al. "Helicobacter pylori infection and gastric juice vitamin C levels: impact of eradication" Dig Dis Sci. March. 1995;40(3):615-621.

Sobala GM, et al. "Effect of eradication of helicobacter pylori on gastric juice ascorbic acid concentrations." Gut. 1993;34:1038-1041.

Chamberlin DT, Perkin HJ. "The level of ascorbic acid in the blood and urine of patients with peptic ulcer." Am J Dig Dis. 1989;5:493.

O'Connor HJ, et al. "Vitamin C in the human stomach: relation to gastric pH, gastroduodenal disease, and possible sources." Gut. 1989;30:436-442.

Dubey SS, et al. "Ascorbic acid, dehydroascorbic acid, glutathione and histamine in peptic ulcer." Indian J Med Res. December,1982;76:859-862.

Esposito R, Valentini R. "Vitamin C and gastroduodenal disorders." Br Med J. April13,1968:118.

Russell RI, et al. "Ascorbic-acid levels in leucocytes of patients with gastrointestinal haemorrhage." Lancet. September14,1968:603-606.

Riggs HE, et al. "The diet and chronic peptic ulcer: its relation to the course of the disorder." JAMA. March4,1944;124(10):639-641.

Portnoy B,. Wilkinson JF. "Vitamin C deficiency in peptic ulceration and hematemesis." Br Med J. March12,1938:554-560.

Vitamin E, Selenium

Al-Moutairy AR, Tariq M. "Effect of vitamin E and selenium on hypothermic restraint stress and chemically-induced ulcers." Dig Dis Sci. June,1996;41(6):1165-1171.

Bulbena O, et al. "Gastroprotective effect of zinc acexamate against damage induced by nonsteroidal anti-inflammatory drugs: a morphological study." Dig Dis Sci. April,1993;38(4):730-739.

Litinskaia EV, et al. "The vitamin E concentration and lipid peroxidation status of patients with peptic ulcer undergoing laser therapy." Vrach Delo. August,1989;8:70-72.

Zinc

Hocke M, et al. "Oral zinc therapy in patients with supposed mild zinc deficiency-a critical review." Gastroenterol. 2001;39:83-88.

Garcia-Plaza A, et al. "A multicenter clinical trial. Zinc acexamate versus famotidine in the treatment of acute duodenal ulcer. Study group of zinc acexamate." Rev Esp Enferm Dig. November,1996;88(11):757-762.

Bandyopadhyay B, et al. "Serum zinc level: a possible index in the pathogenesis of peptic ulcer syndrome." Biochem Mol Biol Int. August,1995;36(5):965-972.

Erzinkian KL, et al. "Zinc metabolism in duodenal ulcer." Ross Med Zh. 1992;(5-12):14-15.

Formmer DJ. "The healing of gastric ulcers by zinc sulphate." Med J Austr. 1975;2:793.

Supplement References

Glutamine

Mitra R, et al. "Inhibition of mast cell population by L-glutamine in aspirin-induced ulceration in rat stomach." Am J Physiol. 1991;261(1 part 1):G65-G70.

Okabe S, et al. "Effects of acetylsalicylic acid (ASA), ASA plus L-glutamine and L-glutamine on healing of chronic gastric ulcer in the rat." Digestion. 1976;14:85-88.

Shive W, et al. "Glutamine in treatment of peptic ulcer." Tex State J Med. 1957;Nov,840-43.

Fatty Acids

Manjari V, Das UN. "Oxidant stress, anti-oxidants, nitric oxide and essential fatty acids in peptic ulcer disease." Prostaglandins Leukot Essent Fatty Acids. 1998;59(6):401-406.

Das UN. "Hypothesis: cis-unsaturated fatty acids as potential anti-peptic ulcer drugs." Prostaglandins Leukot Essent Fatty Acids. 1998;58(5):377-380.

Thompson L, et al. "Inhibitory effect of polyunsaturated fatty acids on the growth of Helicobacter pylori: a possible explanation of the effect of diet on peptic ulceration." Gut. 1994;35(11):1557-1561.

Grant HW, et al. "Duodenal ulcer is associated with low dietary linoleic acid intake." Gut. 1990;31:997-998.

Hollander D, Tarnawski A. "The role of nutrient fatty acids in gastric mucosal protection." in Gastric Cytoprotection; Plenum Publishing Corporation; 1990.

Szabo S, Rogers C. "Diet, ulcer disease, and fish oil." Lancet. January16,1988:119.

Das UN, et al. "Essential fatty acids and peptic ulcer disease." Gut. 1987;2(7):914-916.

Botanical References

Glycyrrhiza

Petry JJ, Hadley SK. "Medicinal herbs: Answers and advice, Part 2." Hosp Pract. August15,2001:55-59.

Goso Y, et al. "Effects of traditional herbal medicine on gastric mucin against ethanol-induced gastric injury in rats." Comp Biochem Physiol. 1996;113C(1):17-21.

Van Marle J, et al. "Deglycyrrhizinised liquorice (DGL) and the renewal of rat stomach epithelium." Eur J Pharmacol. 1981;72:219-225.

Rees WDW, et al. "Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin." Scand J Gastroenterol. 1979;14:605-607.

Bardhan KD, et al. "Clinical trial of deglycyrrhizinised liquorice in gastric ulcer." Gut. September,1978;19(9):779-782.

Brogden RN, et al. "Deglycyrrhizinised liquorice: a report of its pharmacological properties and therapeutic efficacy in peptic ulcer." Drugs. 1974;8:330-339.

Tewari SN, Wilson AK. "Deglycyrrhizinated liquorice in duodenal ulcer." Practitioner. June,1973;210:820-823.

Wilson JAC. "A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient." Br J Clin Pract. December,1972;26(12):563-566.

Turpie AGG, et al. "Clinical trial of deglycyrrhizinised liquorice preparation in peptic ulcer." J Ther Clin Res. 1968;2:2.

Tewari SN, Trembalowicz FC. "Some experience with deglycyrrhizinated liquorice in the treatment of gastric and duodenal ulcers with special reference to its spasmolytic effect." Gut. 1968;9:48-51.

Althea

Lawrence Review of Natural Products: Althea officinalis. December 1991.

Delaveau I, et al. Planta Medica. 1980;40:49.

Geranium

Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy, Vol II. Eclectic Medical Publications; Sandy, OR;1993:347-8.

Echinacea

Balch JF, et al. Prescription for Nutritional Healing, 2nd ed. Avery Publication; NY, NY; 1997:148.

Lawrence Review of Natural Products: Echinacea. January 1990.

Stimpel, et al. "Macrophage activation and induction of macrophage cytotoxicity by purified polysaccharide fractions from the plant Echinacea purpurea." Inf and Immun. December,1984;845-849.

Ulmus

Mabey R, Ed. The New Age Herbalist. Collier Books, Macmillan Publishing Co, NY, NT;1988:117.

Curcuma longa

Ammon and Wahl. "Pharmacology of Curcuma longa." Planta Medica. 1991;57:1-7.

Rafatullah S, et al. "Evaluation of tumeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats", J Ethnopharmacol. 1990;29:25-34.

Satoskar, et al. "Evaluation of anti-inflammatory property of Curcumin in patients with postoperative inflammation." Intr J Clin Pharmacol Ther Toxicol. 1986;12:65,1-2.

Chadra, Gupta. "Anti-inflammatory and anti-arthritic activity of volatile oil of Curcuma longa." Ind J Med Res. 1972;60:138-142.

Hydrastis

Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics, Vol.I. Eclectic Medical Publications; Sandy, OR;1993:417-21.

Homeopathy References

Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.

Other Treatment References

Constitutional Hydrotherapy

Boyle W. Saine A. Lectures in Naturopathic Hydrotherapy. Buckeye Naturopathic Press; East Palestine, OH; 1988:143.

Exercise

Cheng Y, et al. "Physical activity and peptic ulcers: does physical activity reduce the risk of developing peptic ulcers?" WJM. August2000;173:101-107.

NSAIDs

Guslandi M, et al, "Gastric mucosal defenses in the elderly." Gerontol. 1999;45:206-208.

Rodriguez de la Serna A, Diaz-Rubio M. "Multicenter clinical trial of zinc acexamate in the prevention of nonsteroidal antiinflammatory drug induced gastroenteropathy. Spanish study group on NSAID induced gastroenteropathy prevention." J Rheumatol. May,1994;21(5):927-933.

Griffin MR, et al. "Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons." Ann Int Med. February15,1991;114(4):257-263.

Smoking

Aldori WH, et al. "A prospective study of alcohol, smoking, caffeine and the risk of duodenal ulcer in men." Epidemiol. July,1997;8(4):420-424.

Breuer-Katschinski BD, et al. "Smoking as a risk factor for duodenal ulcer relapse." Gastroenterol. 1995;33:509-512.

Kato I, et al. "A prospective study of gastric and duodenal ulcer and its relation to smoking, alcohol, and diet." Am J Epidemiol. 1992;135(5):521-530.

Korman MG, et al. "Influence of cigarette smoking on healing and relapse in duodenal ulcer disease." Gastroenterol. 1983;85(4):871-874.

Stress

Feldman EJ, Sabovich KA. "Stress and peptic ulcer disease." Gastroenterol. 1980;78:1087-9.

Chernov MS, et al. "Stress ulcer: a preventable disease." J Trauma. October,1972;12(10):831-833.

Helicobacter Pylori

Chan FKL, et al. "Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial." Lancet. January5,2002;359:9-13.

Osato MS, et al. "Microflora of gastric biopsies from patients with duodenal ulcer and gastric cancer: a comparative study of patients from Korea, Columbia, and the United States." Dig Dis Sci. October,1998;43(10):2291-2295.

Duggan AE, et al. "Clarification of the link between polyunsaturated fatty acids and Helicobacter pylori- associated duodenal ulcer disease: a dietary intervention study." Br J Nutr. 1997;78:515-522.

Berstad K, Berstad A. "Helicobacter pylori infection in peptic ulcer disease." Scand J Gastroenterol. 1993;28:561-7.