Crataegus oxycantha
(Hawthorne)
Therapeutic Actions:
- Adaptogen specific for the circulatory system
- Cardiotonic
- Collagen stabilizing action
- Cross links collagen fibers
- Improves cardiac metabolism
- Improves coronary circulation by dilating coronary
vessels
- Increases and sustains action of arterioles with principle
influence on the myocardium
- Increases enzyme metabolism in heart muscle
- Increases intracellular vitamin C levels and stabilizes
it
- Increases oxygen utilization by the heart
- Inhibits angiotensin converting enzyme
- Inhibits cAMP phosphodiesterase thus increasing the levels of
cAMP
- Inhibits enzymatic cleavage by enzymes secreted by leukocytes
during inflammation
- Prevents free radical damage
- Prevents the release and synthesis of compounds that promote
inflammation (histamine, prostaglandins, serine proteases,
leukotrienes)
- Regulates distribution of heart rhythm
- Restores myocardial reserve
- Sedative
- Trophorestorative
Clinical Indications:
Contraindications:
Drug/Nutrient Interaction:
- Enhances the effects of digitalis, g-strophanthin, the cardiac herbs, Convallaria majalis and Adonis vernalis, and the cardiac glycosides, digitoxin and digoxin, due to the polymeric procyanidins
Chemical Constituents:
- Amygdalin
- Cardiotonic amines:
Isobutylamine
Omethoxphenylethylamine
Phenylethylamine
Tyramine
- Catechins
- Choline and
acetycholine
- Flavone glycosides
- Flavonoids:
Quercetin
Quercetin-3-galactoside
Vitexin
Vitexin-4'-rhamnoside
- Flavonoid compounds:
Anthocyanidins
Proanthocyanidins
Pectins: triterpene acids - oleanolic, ursolic,
crataegolic
Purine derivatives:
Adenine
Adenosine
Caffeic acid
Guanine
Saponins
Trimethylamine, a circulatory depressant
Vitamin C
Toxicity:
Copyright 1998 - 2008 by L. Vicky Crouse, ND and James S. Reiley, ND. All rights reserved (ISSN 1527-0661).